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Encapsulation of indocyanine green within nano-assembled capsules changes its optical properties — Alliance for NanoHealth
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Mohammad A Yaseen, Jie Yu, Michael S Wong, and Bahman Anvari (2007)

Encapsulation of indocyanine green within nano-assembled capsules changes its optical properties

Proceedings of SPIE 6449.

Indocyanine Green (ICG) is a photosensitive dye frequently used in clinical settings for retinal imaging and measuring cardiac output function. Its low toxicity, high absorption in the near infrared region, and vascular retention have generated much interest in its utility for several therapeutic and diagnostic applications. Its potential, however, is limited by factors such as rapid circulation kinetics and lack of target specificity. Additionally, the optical properties of ICG vary significantly with a wide range of influences such as concentration, solvent, pH, and temperature. In an effort to overcome these limitations and improve ICG's