D O Lapotko, E Lukianova, and A A Oraevsky (2006)
Selective laser nano-thermolysis of human leukemia cells with microbubbles generated around clusters of gold nanoparticles.
Lasers Surg Med. 38(6):631-42.
BACKGROUND AND OBJECTIVE: Previously reported studies on laser nano-thermolysis of cancerous cells demonstrated insufficient efficacy and specificity of malignant cell damage. Safety, that is, absence of damage to normal cells in the course of the laser thermolysis was also low due to less than optimal protocol of cancer cell targeting with nanoparticles (NP). The objective of this study was two-fold: to optimize NP targeting to real tumor (human) cell