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Neuroendocrine modulation of signal transducer and activator of transcription-3 in ovarian cancer. — Alliance for NanoHealth
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CN J Landen, YG Lin, GN Armaiz Pena, PD Das, JM Arevalo, AA Kamat, LY Han, NB Jennings, WA Spannuth, PH Thaker, SK Lutgendorf, CA Savary, AM Sanguino, G Lopez-Berestein, SW Cole, and AK Sood (2007)

Neuroendocrine modulation of signal transducer and activator of transcription-3 in ovarian cancer.

Cancer Res. 67(21):10389-96.

There is growing evidence that chronic stress and other behavioral conditions are associated with cancer pathogenesis and progression, but the mechanisms involved in this association are poorly understood. We examined the effects of two mediators of stress, norepinephrine and epinephrine, on the activation of signal transducer and activator of transcription-3 (STAT3), a transcripti