Researchers from UTMB detail findings in gene therapy

A new study by UTMB researchers published in Gene Therapy (”Composition of PLGA and PEI/DNA nanoparticles improves ultrasound-mediated gene delivery in solid tumors in vivo”) states: “We found that the combination of PLGA/PEI/DNA nanoparticles with ultrasonication substantially enhanced tumor cell transfection in vivo. The overexpression of beta-gal gene was evaluated histochemically and by Western blot analysis.” The study was conducted by Olga.V. Chumakova and colleagues of UTMB’s Center for Biomedical Engineering.